Cargando...
Bioenergetic insufficiencies due to metabolic alterations regulated by PD-1 are an early driver of CD8(+) T cell exhaustion
Dynamic reprogramming of metabolism is essential for T cell effector function and memory formation. However, the regulation of metabolism in exhausted CD8(+) T (Tex) cells is poorly understood. We found that during the first week of chronic lymphocytic choriomeningitis virus (LCMV) infection, before...
Guardado en:
| Publicado en: | Immunity |
|---|---|
| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4988919/ https://ncbi.nlm.nih.gov/pubmed/27496729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.07.008 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|