Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

Buprenorphine has long been classified as a mu analgesic, although its high affinity for other opioid receptor classes and the orphanin FQ/nociceptin ORL(1) receptor may contribute to its other actions. The current studies confirmed a mu mechanism for buprenorphine analgesia, implicating several sub...

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Veröffentlicht in:Synapse
Hauptverfasser: Grinnell, Steven G., Ansonoff, Michael, Marrone, Gina F., Lu, Zhigang, Narayan, Ankita, Xu, Jin, Rossi, Grace, Majumdar, Susruta, Pan, Ying-Xian, Bassoni, Daniel L., Pintar, John, Pasternak, Gavril
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980214/
https://ncbi.nlm.nih.gov/pubmed/27223691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21914
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