The DEG/ENaC cation channel protein UNC-8 drives activity-dependent synapse removal in remodeling GABAergic neurons

Genetic programming and neural activity drive synaptic remodeling in developing neural circuits, but the molecular components that link these pathways are poorly understood. Here we show that the C. elegans Degenerin/Epithelial Sodium Channel (DEG/ENaC) protein, UNC-8, is transcriptionally controlle...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Miller-Fleming, Tyne W, Petersen, Sarah C, Manning, Laura, Matthewman, Cristina, Gornet, Megan, Beers, Allison, Hori, Sayaka, Mitani, Shohei, Bianchi, Laura, Richmond, Janet, Miller, David M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2016
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980115/
https://ncbi.nlm.nih.gov/pubmed/27403890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14599
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items