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Effect of the protease plasmin on C. elegans hyperactive DEG/ENaC channels MEC-4(d) and UNC-8(d)

C. elegans MEC-4 and UNC-8 belong to the DEG/ENaC family of voltage-independent Na(+) channels and have been implicated in mechanosensation and synaptic remodeling. MEC-4 and UNC-8 hyperactive mutants, designated (d) mutants, conduct enhanced currents and cause cell death due to uncontrolled influx...

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Detalles Bibliográficos
Publicado en:MicroPubl Biol
Main Authors: Johnson, Christina K., Miller, David D., Bianchi, Laura
Formato: Artigo
Idioma:Inglês
Publicado: Caltech Library 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223032/
https://ncbi.nlm.nih.gov/pubmed/34189421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17912/micropub.biology.000412
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