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Functional features of the “finger” domain of the DEG/ENaC channels MEC-4 and UNC-8

UNC-8 and MEC-4 are two members of the degenerin/epithelial Na(+) channel (DEG/ENaC) family of voltage-independent Na(+) channels that share a high degree of sequence homology and functional similarity. For example, both can be hyperactivated by genetic mutations [UNC-8(d) and MEC-4(d)] that induce...

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Detalles Bibliográficos
Publicado en:Am J Physiol Cell Physiol
Main Authors: Matthewman, Cristina, Johnson, Christina K., Miller, David M., Bianchi, Laura
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139502/
https://ncbi.nlm.nih.gov/pubmed/29694233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00297.2017
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