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Ca(2+) permeability and Na(+) conductance in cellular toxicity caused by hyperactive DEG/ENaC channels
Hyperactivated DEG/ENaC channels cause neuronal death mediated by intracellular Ca(2+) overload. Mammalian ASIC1a channels and MEC-4(d) neurotoxic channels in Caenorhabditis elegans both conduct Na(+) and Ca(2+), raising the possibility that direct Ca(2+) influx through these channels contributes to...
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| Publicado no: | Am J Physiol Cell Physiol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206307/ https://ncbi.nlm.nih.gov/pubmed/27760755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00247.2016 |
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