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Functional features of the “finger” domain of the DEG/ENaC channels MEC-4 and UNC-8
UNC-8 and MEC-4 are two members of the degenerin/epithelial Na(+) channel (DEG/ENaC) family of voltage-independent Na(+) channels that share a high degree of sequence homology and functional similarity. For example, both can be hyperactivated by genetic mutations [UNC-8(d) and MEC-4(d)] that induce...
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Publicado no: | Am J Physiol Cell Physiol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139502/ https://ncbi.nlm.nih.gov/pubmed/29694233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00297.2017 |
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