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Insights into the molecular determinants of proton-inhibition in an acid-inactivated DEG/ENaC channel
Mammalian ASIC channels of the DEG/ENaC superfamily are gated by extracellular protons and function to mediate touch and pain sensitivity, learning and memory, and fear conditioning. The recently solved crystal structure of chicken ASIC1a and preliminary functional studies suggested that a highly ne...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764801/ https://ncbi.nlm.nih.gov/pubmed/19769407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9014902 |
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