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Insights into the molecular determinants of proton-inhibition in an acid-inactivated DEG/ENaC channel

Mammalian ASIC channels of the DEG/ENaC superfamily are gated by extracellular protons and function to mediate touch and pain sensitivity, learning and memory, and fear conditioning. The recently solved crystal structure of chicken ASIC1a and preliminary functional studies suggested that a highly ne...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Ying, Bianchi, Laura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764801/
https://ncbi.nlm.nih.gov/pubmed/19769407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9014902
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