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Insight into DEG/ENaC Channel Gating from Genetics and Structure

The founding members of the superfamily of DEG/ENaC ion channel proteins are C. elegans proteins that form mechanosensitive channels in touch and pain receptors. For more than a decade, the research community has used mutagenesis to identify motifs that regulate gating. This review integrates insigh...

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Autori principali: Eastwood, Amy L., Goodman, Miriam B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012085/
https://ncbi.nlm.nih.gov/pubmed/23026751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00006.2012
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