DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor

Many nociceptors detect mechanical cues, but the ion channels responsible for mechanotransduction in these sensory neurons remain obscure. Using in vivo recordings and genetic dissection, we identified the DEG/ENaC protein, DEG-1, as the major mechanotransduction channel in ASH, a polymodal nocicept...

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Detalhes bibliográficos
Main Authors: Geffeney, Shana L., Cueva, Juan G., Glauser, Dominique A., Doll, Joseph C., Lee, Tim Hau-Chen, Montoya, Misty, Karania, Snetu, Garakani, Arman M., Pruitt, Beth L., Goodman, Miriam B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170654/
https://ncbi.nlm.nih.gov/pubmed/21903078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.06.038
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