DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor

Many nociceptors detect mechanical cues, but the ion channels responsible for mechanotransduction in these sensory neurons remain obscure. Using in vivo recordings and genetic dissection, we identified the DEG/ENaC protein, DEG-1, as the major mechanotransduction channel in ASH, a polymodal nocicept...

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Detaylı Bibliyografya
Asıl Yazarlar: Geffeney, Shana L., Cueva, Juan G., Glauser, Dominique A., Doll, Joseph C., Lee, Tim Hau-Chen, Montoya, Misty, Karania, Snetu, Garakani, Arman M., Pruitt, Beth L., Goodman, Miriam B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170654/
https://ncbi.nlm.nih.gov/pubmed/21903078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.06.038
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