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DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor
Many nociceptors detect mechanical cues, but the ion channels responsible for mechanotransduction in these sensory neurons remain obscure. Using in vivo recordings and genetic dissection, we identified the DEG/ENaC protein, DEG-1, as the major mechanotransduction channel in ASH, a polymodal nocicept...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170654/ https://ncbi.nlm.nih.gov/pubmed/21903078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.06.038 |
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