Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors

Polymodal nociceptors detect noxious stimuli including harsh touch, toxic chemicals, and extremes of heat and cold. The molecular mechanisms by which nociceptors are able to sense multiple qualitatively distinct stimuli are not well-understood. We show here that the C. elegans PVD neurons are muliti...

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Bibliografiska uppgifter
Huvudupphovsmän: Chatzigeorgiou, Marios, Yoo, Sungjae, Watson, Joseph D., Lee, Wei-Hsiang, Spencer, W. Clay, Kindt, Katie S., Hwang, Sun Wook, Miller, David M., Treinin, Millet, Driscoll, Monica, Schafer, William R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975101/
https://ncbi.nlm.nih.gov/pubmed/20512132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2581
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