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Spliceosomal DEAH-box ATPases remodel pre-mRNA to activate alternative splice sites
During pre-mRNA splicing, a central step in the expression and regulation of eukaryotic genes, the spliceosome selects splice sites for intron excision and exon ligation. In doing so, the spliceosome must distinguish optimal from suboptimal splice sites. At the catalytic stage of splicing, suboptima...
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| Опубликовано в: : | Cell |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979991/ https://ncbi.nlm.nih.gov/pubmed/26919433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.01.025 |
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