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Crystal structure of the spliceosomal DEAH-box ATPase Prp2

The DEAH-box ATPase Prp2 plays a key role in the activation of the spliceosome as it promotes the transition from the B(act) to the catalytically active B* spliceosome. Here, four crystal structures of Prp2 are reported: one of the nucleotide-free state and three different structures of the ADP-boun...

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Bibliografski detalji
Izdano u:Acta Crystallogr D Struct Biol
Glavni autori: Schmitt, Andreas, Hamann, Florian, Neumann, Piotr, Ficner, Ralf
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038383/
https://ncbi.nlm.nih.gov/pubmed/29968674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318006356
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