Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2

The spliceosome consists of five small RNAs and more than 100 proteins. Almost 50% of the human spliceosomal proteins were predicted to be intrinsically disordered or to contain disordered regions, among them the G-patch protein Spp2. The G-patch region of Spp2 binds to the DEAH-box ATPase Prp2, and...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Hamann, Florian, Schmitt, Andreas, Favretto, Filippo, Hofele, Romina, Neumann, Piotr, Xiang, ShengQi, Urlaub, Henning, Zweckstetter, Markus, Ficner, Ralf
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022188/
https://ncbi.nlm.nih.gov/pubmed/31974312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907960117
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы