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Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry

Splicing of precursor messenger RNA is a hallmark of eukaryotic cells, which is carried out by the spliceosome, a multi-megadalton ribonucleoprotein machinery. The splicing reaction removes non-coding regions (introns) and ligates coding regions (exons). The spliceosome is a highly dynamic ribonucle...

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Detalhes bibliográficos
Main Authors: Christian, Henning, Hofele, Romina V., Urlaub, Henning, Ficner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902948/
https://ncbi.nlm.nih.gov/pubmed/24165877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt985
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