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Structural insights into the mechanism of the DEAH-box RNA helicase Prp43

The DEAH-box helicase Prp43 is a key player in pre-mRNA splicing as well as the maturation of rRNAs. The exact modus operandi of Prp43 and of all other spliceosomal DEAH-box RNA helicases is still elusive. Here, we report crystal structures of Prp43 complexes in different functional states and the a...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Tauchert, Marcel J, Fourmann, Jean-Baptiste, Lührmann, Reinhard, Ficner, Ralf
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262380/
https://ncbi.nlm.nih.gov/pubmed/28092261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21510
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