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Structural insights into the mechanism of the DEAH-box RNA helicase Prp43
The DEAH-box helicase Prp43 is a key player in pre-mRNA splicing as well as the maturation of rRNAs. The exact modus operandi of Prp43 and of all other spliceosomal DEAH-box RNA helicases is still elusive. Here, we report crystal structures of Prp43 complexes in different functional states and the a...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5262380/ https://ncbi.nlm.nih.gov/pubmed/28092261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21510 |
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