The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction

The DEAH-box NTPase Prp43 and its cofactors Ntr1 and Ntr2 form the NTR complex and are required for disassembling intron-lariat spliceosomes (ILS) and defective earlier spliceosomes. However, the Prp43 binding site in the spliceosome and its target(s) are unknown. We show that Prp43 fused to Ntr1�...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fourmann, Jean-Baptiste, Dybkov, Olexandr, Agafonov, Dmitry E, Tauchert, Marcel J, Urlaub, Henning, Ficner, Ralf, Fabrizio, Patrizia, Lührmann, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866824/
https://ncbi.nlm.nih.gov/pubmed/27115347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15564
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados