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Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28
The DEAD-box protein Prp28 is essential for pre-mRNA splicing as it plays a key role in the formation of an active spliceosome. Prp28 participates in the release of the U1 snRNP from the 5′-splice site during association of the U5·U4/U6 tri-snRNP, which is a crucial step in the transition from a pre...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051504/ https://ncbi.nlm.nih.gov/pubmed/24914973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714006439 |
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