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DEAH-Box RNA Helicases in Pre-mRNA Splicing

In eukaryotic cells, pre-mRNA splicing is catalyzed by the spliceosome, a highly dynamic molecular machinery that undergoes dramatic conformational and compositional rearrangements throughout the splicing cycle. These crucial rearrangements are largely driven by eight DExD/H-box RNA helicases. Inter...

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Detalhes bibliográficos
Publicado no:Trends Biochem Sci
Main Authors: De Bortoli, Francesca, Espinosa, Sara, Zhao, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112905/
https://ncbi.nlm.nih.gov/pubmed/33272784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2020.10.006
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