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RNA helicase dynamics in pre-mRNA splicing

The DExH-box NTPase/helicase Prp22p plays two important roles in pre-mRNA splicing. It promotes the second transesterification reaction and then catalyzes the ATP-dependent release of mature mRNA from the spliceosome. Evidence that helicase activity is important emerged from the analysis of Prp22p m...

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Detalhes bibliográficos
Main Authors: Schwer, Beate, Meszaros, Tamar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305851/
https://ncbi.nlm.nih.gov/pubmed/11101530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6582
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