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Spliceosome discards intermediates via the DEAH box ATPase Prp43p
To promote fidelity in nuclear pre-mRNA splicing, the spliceosome rejects and discards suboptimal substrates that have engaged the spliceosome. Whereas DExD/H box ATPases have been implicated in rejecting suboptimal substrates, the mechanism for discarding suboptimal substrates has remained obscure....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890470/ https://ncbi.nlm.nih.gov/pubmed/20463285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906022107 |
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