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Exon ligation is proofread by the DExD/H-box ATPase Prp22p
To produce mRNA, the spliceosome excises introns from pre-mRNA and splices the flanking exons. To establish fidelity the spliceosome discriminates against aberrant introns, but our understanding of such fidelity mechanisms is limited. Here we show that an ATP-dependent activity represses formation o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729281/ https://ncbi.nlm.nih.gov/pubmed/16680161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1093 |
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