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Crystallization and preliminary X-ray diffraction analysis of the C-terminal domain of the human spliceosomal DExD/H-box protein hPrp22

The Homo sapiens DExD/H-box protein hPrp22 is a crucial component of the eukaryotic pre-mRNA splicing machinery. Within the splicing cycle, it is involved in the ligation of exons and generation of the lariat and it additionally catalyzes the release of mature mRNA from the spliceosomal U5 snRNP. Th...

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Detalhes bibliográficos
Main Authors: Kudlinzki, Denis, Nagel, Christian, Ficner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795611/
https://ncbi.nlm.nih.gov/pubmed/19724143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109031844
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