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Crystallization and preliminary X-ray diffraction analysis of the C-terminal domain of the human spliceosomal DExD/H-box protein hPrp22

The Homo sapiens DExD/H-box protein hPrp22 is a crucial component of the eukaryotic pre-mRNA splicing machinery. Within the splicing cycle, it is involved in the ligation of exons and generation of the lariat and it additionally catalyzes the release of mature mRNA from the spliceosomal U5 snRNP. Th...

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Autors principals: Kudlinzki, Denis, Nagel, Christian, Ficner, Ralf
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795611/
https://ncbi.nlm.nih.gov/pubmed/19724143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109031844
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