Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

Targeted therapy for metastatic colorectal carcinoma consists of anti-EGFR therapy for patients with RAS/RAF wild-type tumors. However, the response rate remains low, suggesting the presence of alternative drivers possibly also representing potential therapeutic targets. We investigated receptor tyr...

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Publicado en:Mol Cancer Res
Main Authors: Hechtman, Jaclyn F., Zehir, Ahmet, Yaeger, Rona, Wang, Lu, Middha, Sumit, Zheng, Tao, Hyman, David M., Solit, David, Arcila, Maria E., Borsu, Laetitia, Shia, Jinru, Vakiani, Efsevia, Saltz, Leonard, Ladanyi, Marc
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972456/
https://ncbi.nlm.nih.gov/pubmed/26660078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0392-T
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