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Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

Targeted therapy for metastatic colorectal carcinoma consists of anti-EGFR therapy for patients with RAS/RAF wild-type tumors. However, the response rate remains low, suggesting the presence of alternative drivers possibly also representing potential therapeutic targets. We investigated receptor tyr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Cancer Res
Main Authors: Hechtman, Jaclyn F., Zehir, Ahmet, Yaeger, Rona, Wang, Lu, Middha, Sumit, Zheng, Tao, Hyman, David M., Solit, David, Arcila, Maria E., Borsu, Laetitia, Shia, Jinru, Vakiani, Efsevia, Saltz, Leonard, Ladanyi, Marc
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972456/
https://ncbi.nlm.nih.gov/pubmed/26660078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0392-T
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