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Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

Targeted therapy for metastatic colorectal carcinoma consists of anti-EGFR therapy for patients with RAS/RAF wild-type tumors. However, the response rate remains low, suggesting the presence of alternative drivers possibly also representing potential therapeutic targets. We investigated receptor tyr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer Res
Egile Nagusiak: Hechtman, Jaclyn F., Zehir, Ahmet, Yaeger, Rona, Wang, Lu, Middha, Sumit, Zheng, Tao, Hyman, David M., Solit, David, Arcila, Maria E., Borsu, Laetitia, Shia, Jinru, Vakiani, Efsevia, Saltz, Leonard, Ladanyi, Marc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972456/
https://ncbi.nlm.nih.gov/pubmed/26660078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0392-T
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