Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival

Here comprehensive analysis was performed on the molecular and clinical features of colorectal carcinoma (CRC) harboring chromosome 20q amplification. Tumor and normal DNA from patients with advanced CRC underwent next generation sequencing (NGS) via MSK-IMPACT and a subset of case samples were subj...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Ptashkin, Ryan N, Pagan, Carlos, Yaeger, Rona, Middha, Sumit, Shia, Jinru, O’Rourke, Kevin P, Berger, Michael F, Wang, Lu, Cimera, Robert, Wang, Jiajing, Klimstra, David S., Saltz, Leonard, Ladanyi, Marc, Zehir, Ahmet, Hechtman, Jaclyn F
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588907/
https://ncbi.nlm.nih.gov/pubmed/28184012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0352
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