ADAMTS13 Autoantibodies Cloned from Patients with Acquired Thrombotic Thrombocytopenic Purpura: 1. Structural and functional characterization in vitro

BACKGROUND: Acquired thrombotic thrombocytopenia purpura (TTP) is a life-threatening illness caused by autoantibodies that decrease the activity of ADAMTS13, the von Willebrand Factor cleaving protease. Despite efficacy of plasma exchange, mortality remains high and relapse is common. Improved thera...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Transfusion
Autores principales: Ostertag, Eric M., Kacir, Stephen, Thiboutot, Michelle, Gulendran, Gayathri, Zheng, X. Long, Cines, Douglas B., Siegel, Don L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938786/
https://ncbi.nlm.nih.gov/pubmed/27040144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.13584
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares