ADAMTS13 Autoantibodies Cloned from Patients with Acquired Thrombotic Thrombocytopenic Purpura: 1. Structural and functional characterization in vitro

BACKGROUND: Acquired thrombotic thrombocytopenia purpura (TTP) is a life-threatening illness caused by autoantibodies that decrease the activity of ADAMTS13, the von Willebrand Factor cleaving protease. Despite efficacy of plasma exchange, mortality remains high and relapse is common. Improved thera...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: Ostertag, Eric M., Kacir, Stephen, Thiboutot, Michelle, Gulendran, Gayathri, Zheng, X. Long, Cines, Douglas B., Siegel, Don L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938786/
https://ncbi.nlm.nih.gov/pubmed/27040144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.13584
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados