Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α

Restriction factors and pattern recognition receptors are important components of intrinsic cellular defenses against viral infection. Mammalian TRIM5α proteins are restriction factors and receptors that target the capsid cores of retroviruses and activate ubiquitin-dependent antiviral responses upo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Wagner, Jonathan M, Roganowicz, Marcin D, Skorupka, Katarzyna, Alam, Steven L, Christensen, Devin, Doss, Ginna, Wan, Yueping, Frank, Gabriel A, Ganser-Pornillos, Barbie K, Sundquist, Wesley I, Pornillos, Owen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2016
Gaiak:
Biochemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936894/
https://ncbi.nlm.nih.gov/pubmed/27253059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16309
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