TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition

Restriction factors are important components of intrinsic cellular defense mechanisms against viral pathogens. TRIM5α is a restriction factor that intercepts the incoming capsid cores of retroviruses such as HIV and provides an effective species-specific barrier to retroviral infection. The TRIM5α S...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Roganowicz, Marcin D., Komurlu, Sevnur, Mukherjee, Santanu, Plewka, Jacek, Alam, Steven L., Skorupka, Katarzyna A., Wan, Yueping, Dawidowski, Damian, Cafiso, David S., Ganser-Pornillos, Barbie K., Campbell, Edward M., Pornillos, Owen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667893/
https://ncbi.nlm.nih.gov/pubmed/29040325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006686
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