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Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α
Restriction factors and pattern recognition receptors are important components of intrinsic cellular defenses against viral infection. Mammalian TRIM5α proteins are restriction factors and receptors that target the capsid cores of retroviruses and activate ubiquitin-dependent antiviral responses upo...
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| Vydáno v: | eLife |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936894/ https://ncbi.nlm.nih.gov/pubmed/27253059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16309 |
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