Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α

Restriction factors and pattern recognition receptors are important components of intrinsic cellular defenses against viral infection. Mammalian TRIM5α proteins are restriction factors and receptors that target the capsid cores of retroviruses and activate ubiquitin-dependent antiviral responses upo...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Wagner, Jonathan M, Roganowicz, Marcin D, Skorupka, Katarzyna, Alam, Steven L, Christensen, Devin, Doss, Ginna, Wan, Yueping, Frank, Gabriel A, Ganser-Pornillos, Barbie K, Sundquist, Wesley I, Pornillos, Owen
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2016
主題:
Biochemistry
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936894/
https://ncbi.nlm.nih.gov/pubmed/27253059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16309
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