Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α

Restriction factors and pattern recognition receptors are important components of intrinsic cellular defenses against viral infection. Mammalian TRIM5α proteins are restriction factors and receptors that target the capsid cores of retroviruses and activate ubiquitin-dependent antiviral responses upo...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Wagner, Jonathan M, Roganowicz, Marcin D, Skorupka, Katarzyna, Alam, Steven L, Christensen, Devin, Doss, Ginna, Wan, Yueping, Frank, Gabriel A, Ganser-Pornillos, Barbie K, Sundquist, Wesley I, Pornillos, Owen
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Biochemistry
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936894/
https://ncbi.nlm.nih.gov/pubmed/27253059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16309
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