General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins

Restriction factors are intrinsic cellular defense proteins that have evolved to block microbial infections. Retroviruses such as HIV-1 are restricted by TRIM5 proteins, which recognize the viral capsid shell that surrounds, organizes, and protects the viral genome. TRIM5α uses a SPRY domain to bind...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Wagner, Jonathan M., Christensen, Devin E., Bhattacharya, Akash, Dawidziak, Daria M., Roganowicz, Marcin D., Wan, Yueping, Pumroy, Ruth A., Demeler, Borries, Ivanov, Dmitri N., Ganser-Pornillos, Barbie K., Sundquist, Wesley I., Pornillos, Owen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790955/
https://ncbi.nlm.nih.gov/pubmed/29187540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01563-17
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