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Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro
During the first half of the viral life cycle, HIV-1 reverse transcribes its RNA genome and integrates the double-stranded DNA copy into a host cell chromosome. Despite progress in characterizing and inhibiting these processes, in situ mechanistic and structural studies remain challenging. This is b...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8022914/ https://ncbi.nlm.nih.gov/pubmed/33033190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc8420 |
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