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Restriction of HIV-1 and retroviruses by TRIM5
Mammalian cells express a variety of innate immune proteins called restriction factors that defend against invading retroviruses such as HIV-1. Two members of the tripartite motif protein family – TRIM5α and TRIMCyp – were identified in 2004 as restriction factors that recognize and inactivate the c...
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| Veröffentlicht in: | Nat Rev Microbiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858284/ https://ncbi.nlm.nih.gov/pubmed/31312031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41579-019-0225-2 |
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