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Restriction of HIV-1 and retroviruses by TRIM5

Mammalian cells express a variety of innate immune proteins called restriction factors that defend against invading retroviruses such as HIV-1. Two members of the tripartite motif protein family – TRIM5α and TRIMCyp – were identified in 2004 as restriction factors that recognize and inactivate the c...

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Detalhes bibliográficos
Publicado no:Nat Rev Microbiol
Main Authors: Ganser-Pornillos, Barbie K., Pornillos, Owen
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858284/
https://ncbi.nlm.nih.gov/pubmed/31312031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41579-019-0225-2
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