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Retrovirus restriction by TRIM5α: RINGside at a cage fight

The restriction factor TRIM5α recognizes incoming retroviral capsids and blocks virus replication. In this issue of Cell Host and Microbe, Fletcher et al. (2018) show how the TRIM5α RING domain mediates formation of various ubiquitin conjugates that differentially regulate TRIM5α turnover, inhibitio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Host Microbe
Egile Nagusiak: Sundquist, Wesley I., Pornillos, Owen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464375/
https://ncbi.nlm.nih.gov/pubmed/30543772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.11.013
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