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Retrovirus restriction by TRIM5α: RINGside at a cage fight
The restriction factor TRIM5α recognizes incoming retroviral capsids and blocks virus replication. In this issue of Cell Host and Microbe, Fletcher et al. (2018) show how the TRIM5α RING domain mediates formation of various ubiquitin conjugates that differentially regulate TRIM5α turnover, inhibitio...
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| Publicat a: | Cell Host Microbe |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6464375/ https://ncbi.nlm.nih.gov/pubmed/30543772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.11.013 |
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