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Retrovirus restriction by TRIM5α: RINGside at a cage fight

The restriction factor TRIM5α recognizes incoming retroviral capsids and blocks virus replication. In this issue of Cell Host and Microbe, Fletcher et al. (2018) show how the TRIM5α RING domain mediates formation of various ubiquitin conjugates that differentially regulate TRIM5α turnover, inhibitio...

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Bibliografische gegevens
Gepubliceerd in:Cell Host Microbe
Hoofdauteurs: Sundquist, Wesley I., Pornillos, Owen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464375/
https://ncbi.nlm.nih.gov/pubmed/30543772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.11.013
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