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Hexagonal assembly of a restricting TRIM5α protein
TRIM5α proteins are restriction factors that protect mammalian cells from retroviral infections by binding incoming viral capsids, accelerating their dissociation, and preventing reverse transcription of the viral genome. Individual TRIM5 isoforms can often protect cells against a broad range of ret...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021009/ https://ncbi.nlm.nih.gov/pubmed/21187419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013426108 |
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