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Hexagonal assembly of a restricting TRIM5α protein

TRIM5α proteins are restriction factors that protect mammalian cells from retroviral infections by binding incoming viral capsids, accelerating their dissociation, and preventing reverse transcription of the viral genome. Individual TRIM5 isoforms can often protect cells against a broad range of ret...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ganser-Pornillos, Barbie K., Chandrasekaran, Viswanathan, Pornillos, Owen, Sodroski, Joseph G., Sundquist, Wesley I., Yeager, Mark
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021009/
https://ncbi.nlm.nih.gov/pubmed/21187419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013426108
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