Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

Deregulated cellular metabolism is a hallmark of tumors. Cancer cells increase glucose and glutamine flux to provide energy needs and macromolecular synthesis demands. Several studies have been focused on the importance of glycolysis and pentose phosphate pathway. However, a neglected but very impor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lucena, Miguel C., Carvalho-Cruz, Patricia, Donadio, Joana L., Oliveira, Isadora A., de Queiroz, Rafaela M., Marinho-Carvalho, Monica M., Sola-Penna, Mauro, de Paula, Iron F., Gondim, Katia C., McComb, Mark E., Costello, Catherine E., Whelan, Stephen A., Todeschini, Adriane R., Dias, Wagner B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933211/
https://ncbi.nlm.nih.gov/pubmed/27129262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729236
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