Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

Deregulated cellular metabolism is a hallmark of tumors. Cancer cells increase glucose and glutamine flux to provide energy needs and macromolecular synthesis demands. Several studies have been focused on the importance of glycolysis and pentose phosphate pathway. However, a neglected but very impor...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Lucena, Miguel C., Carvalho-Cruz, Patricia, Donadio, Joana L., Oliveira, Isadora A., de Queiroz, Rafaela M., Marinho-Carvalho, Monica M., Sola-Penna, Mauro, de Paula, Iron F., Gondim, Katia C., McComb, Mark E., Costello, Catherine E., Whelan, Stephen A., Todeschini, Adriane R., Dias, Wagner B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933211/
https://ncbi.nlm.nih.gov/pubmed/27129262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729236
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