Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells

The Hexosamine Biosynthetic Pathway (HBP) is a branch of glycolysis responsible for the production of a key substrate for protein glycosylation, UDP-GlcNAc. Cancer cells present altered glucose metabolism and aberrant glycosylation, pointing to alterations on HBP. Recently it was demonstrated that H...

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Veröffentlicht in:Front Oncol
Hauptverfasser: de Queiroz, Rafaela Muniz, Oliveira, Isadora Araújo, Piva, Bruno, Bouchuid Catão, Felipe, da Costa Rodrigues, Bruno, da Costa Pascoal, Adriana, Diaz, Bruno Lourenço, Todeschini, Adriane Regina, Caarls, Michelle Botelho, Dias, Wagner Barbosa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411693/
https://ncbi.nlm.nih.gov/pubmed/30891426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00116
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