Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

Deregulated cellular metabolism is a hallmark of tumors. Cancer cells increase glucose and glutamine flux to provide energy needs and macromolecular synthesis demands. Several studies have been focused on the importance of glycolysis and pentose phosphate pathway. However, a neglected but very impor...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Lucena, Miguel C., Carvalho-Cruz, Patricia, Donadio, Joana L., Oliveira, Isadora A., de Queiroz, Rafaela M., Marinho-Carvalho, Monica M., Sola-Penna, Mauro, de Paula, Iron F., Gondim, Katia C., McComb, Mark E., Costello, Catherine E., Whelan, Stephen A., Todeschini, Adriane R., Dias, Wagner B.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Glycobiology and Extracellular Matrices
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933211/
https://ncbi.nlm.nih.gov/pubmed/27129262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729236
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