(18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier

Efflux transporters at the blood-brain barrier can decrease the entry of drugs and increase the removal of those molecules able to bypass the transporter. We previously hypothesized that (18)F-FCWAY, a radioligand for the serotonin 5-HT(1A) receptor, is a weak substrate for permeability glycoprotein...

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Pubblicato in:Neuroimage
Autori principali: Liow, Jeih-San, Zoghbi, Sami S., Hu, Shuo, Hall, Matthew D., Hines, Christina S., Shetty, H. Umesha, Araneta, Maria D., Page, Emily M., Pike, Victor W., Kreisl, William C., Herscovitch, Peter, Gottesman, Michael M., Theodore, William H., Innis, Robert B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928098/
https://ncbi.nlm.nih.gov/pubmed/27211474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.05.045
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