Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland

Large-scale sequencing studies are rapidly identifying putative oncogenic mutations in human tumors. However, discrimination between passenger and driver events in tumorigenesis remains challenging and requires in vivo validation studies in reliable animal models of human cancer. In this study, we d...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Genes Dev
Главные авторы: Annunziato, Stefano, Kas, Sjors M., Nethe, Micha, Yücel, Hatice, Del Bravo, Jessica, Pritchard, Colin, Bin Ali, Rahmen, van Gerwen, Bas, Siteur, Bjørn, Drenth, Anne Paulien, Schut, Eva, van de Ven, Marieke, Boelens, Mirjam C., Klarenbeek, Sjoerd, Huijbers, Ivo J., van Miltenburg, Martine H., Jonkers, Jos
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2016
Предметы:
Resource/Methodology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926868/
https://ncbi.nlm.nih.gov/pubmed/27340177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.279190.116
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы