Truncated ASPP2 drives initiation and progression of invasive lobular carcinoma via distinct mechanisms

Invasive lobular carcinoma (ILC) accounts for 8-14% of all breast cancer cases. The main hallmark of ILCs is the functional loss of the cell-cell adhesion protein E-cadherin. Nonetheless, loss of E-cadherin alone does not predispose mice to mammary tumor development indicating that additional pertur...

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發表在:Cancer Res
Main Authors: Schipper, Koen, Drenth, Anne Paulien, van der Burg, Eline, Cornelissen, Samuel P., Klarenbeek, Sjoerd, Nethe, Micha, Jonkers, Jos
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611216/
https://ncbi.nlm.nih.gov/pubmed/32060147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3607
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