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Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin
E-cadherin (CDH1) is a master regulator of epithelial cell adherence junctions and a well-established tumor suppressor in Invasive Lobular Carcinoma (ILC). Intriguingly, somatic inactivation of E-cadherin alone in mouse mammary epithelial cells (MMECs) is insufficient to induce tumor formation. Here...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707221/ https://ncbi.nlm.nih.gov/pubmed/31444332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11716-6 |
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