p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice

Loss of E-cadherin expression is causal to the development of invasive lobular breast carcinoma (ILC). E-cadherin loss leads to dismantling of the adherens junction and subsequent translocation of p120-catenin (p120) to the cytosol and nucleus. Although p120 is critical for the metastatic potential...

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Publicat a:J Mammary Gland Biol Neoplasia
Autors principals: Tenhagen, Milou, Klarenbeek, Sjoerd, Braumuller, Tanya M., Hofmann, Ilse, van der Groep, Petra, ter Hoeve, Natalie, van der Wall, Elsken, Jonkers, Jos, Derksen, Patrick W. B.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159444/
https://ncbi.nlm.nih.gov/pubmed/27411687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-016-9358-3
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